Startup Powering Medical In Japan

Imagine being able to reverse vision loss with a single injection. A Japanese startup is working on a simple gene therapy that would improve the quality of life for thousands of people with retinitis pigmentosa, a disease that causes blindness. Fostering such innovative startups and driving technological development to address global issues is one of the major pillars of Japan’s growth strategy. The Government of Japan plans to establish a 10 trillion yen ($86.5 billion) university fund to support research, while building an ecosystem that connects entrepreneurs, universities, financing and public institutions to facilitate startups. Some local governments have already formed ecosystems that take advantage of regional characteristics. One is Kobe, a city that recovered from a great earthquake to become the largest biomedical innovation hub in Japan.

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Gene therapy for blindness

Retinitis pigmentosa is the second leading cause of blindness in Japan, affecting 70,000 Japanese and one in 3,000 to one in 5,000 people worldwide. Photoreceptor cells in the back of the eye gradually degenerate, causing vision loss and in some cases tunnel vision. There is no cure, and people with the condition must adapt to visually impaired living. But a Japanese startup is developing a treatment that could significantly restore vision with one injection. Restore Vision is just one of dozens of new companies doing research in Kobe’s biomedical ecosystem.

Planting seeds for new business

Miyazaki helped put the startup on a firm footing for growth. He formerly worked at science and technology company Leave a Nest, which introduced Restore Vision to Startup Creative Lab (SCL). SCL is a shared laboratory in the Kobe Biomedical Innovation Cluster (KBIC) that began incubating Restore Vision’s R&D operations in 2021. There are a number of hospitals in KBIC including Kobe Eye Center, an ophthalmology hospital that provides total support from basic research to treatment and rehabilitation.

Strengthening a biomedical powerhouse

SCL acts like a life sciences incubator in the greater KBIC. The cluster was launched in 1998 as one of the projects to speed recovery following the devastating Great Hanshin Earthquake three years earlier. Its main objective is to contribute to global medical care.